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Quantitation of integrin receptor agonism by fluorescence lifetime imaging

Both spatiotemporal analyses of adhesion signalling and the development of pharmacological inhibitors of integrin adhesion receptors currently suffer from the lack of an assay to measure integrin-effector binding and the response of these interactions to agonists. Here, we have expressed integrin-GF...

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Detalhes bibliográficos
Main Authors: Parsons, Maddy, Messent, Anthea J., Humphries, Jonathan D., Deakin, Nicholas O., Humphries, Martin J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3328206/
https://ncbi.nlm.nih.gov/pubmed/18216331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.018440
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