Poly(ADP-Ribose) Polymerase-1 Inhibition by Arsenite Promotes the Survival of Cells With Unrepaired DNA Lesions Induced by UV Exposure

Human arsenic exposure is associated with increased risk of skin cancer, and arsenite greatly enhances ultraviolet (UV)-induced skin tumors in a mouse model of carcinogenesis. Inhibition of DNA repair is one proposed mechanism for the observed cocarcinogenicity. We have previously demonstrated that...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Qin, Xu-Jun, Liu, Wenlan, Li, Ying-Na, Sun, Xi, Hai, Chun-Xu, Hudson, Laurie G., Liu, Ke Jian
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Environmental Toxicology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3327874/
https://ncbi.nlm.nih.gov/pubmed/22387748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfs099
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados