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Course of Improvement in Depressive Symptoms to a Single Intravenous Infusion of Ketamine vs Add-on Riluzole: Results from a 4-Week, Double-Blind, Placebo-Controlled Study

The N-methyl--aspartate antagonist ketamine has rapid antidepressant effects in patients with treatment-resistant major depression (TRD); these effects have been reported to last for 1 week in some patients. However, the extent and duration of this antidepressant effect over longer periods has not b...

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Detalhes bibliográficos
Main Authors: Ibrahim, Lobna, DiazGranados, Nancy, Franco-Chaves, Jose, Brutsche, Nancy, Henter, Ioline D, Kronstein, Phillip, Moaddel, Ruin, Wainer, Irving, Luckenbaugh, David A, Manji, Husseini K, Zarate, Carlos A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3327857/
https://ncbi.nlm.nih.gov/pubmed/22298121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2011.338
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