A γ-Tocopherol-Rich Mixture of Tocopherols Maintains Nrf2 Expression in Prostate Tumors of TRAMP Mice via Epigenetic Inhibition of CpG Methylation(2)

Nuclear factor-erythroid 2-related factor 2 (Nrf2) plays a pivotal role in maintaining cellular redox homeostasis and eliminating reactive toxic species. Nrf2 is epigenetically suppressed due to CpG hypermethylation in prostate tumors from the transgenic adenocarcinoma of the mouse prostate (TRAMP)...

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Bibliografske podrobnosti
Main Authors: Huang, Ying, Khor, Tin Oo, Shu, Limin, Saw, Constance Lay-Lay, Wu, Tien-Yuan, Suh, Nanjoo, Yang, Chung S., Kong, Ah-Ng Tony
Format: Artigo
Jezik:Inglês
Izdano: American Society for Nutrition 2012
Teme:
Biochemical, Molecular, and Genetic Mechanisms
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3327740/
https://ncbi.nlm.nih.gov/pubmed/22457388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3945/jn.111.153114
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