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Ambra1: A Parkin-binding protein involved in mitophagy

Mutations in the gene for the E3 ubiquitin ligase Parkin are the most prevalent cause of autosomal recessive Parkinson disease (PD), an incurable neurodegenerative disorder. Parkin surveys mitochondrial quality by translocating to depolarized mitochondria and inducing their selective macroautophagic...

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Autors principals: Van Humbeeck, Cindy, Cornelissen, Tom, Vandenberghe, Wim
Format: Artigo
Idioma:Inglês
Publicat: Landes Bioscience 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3327619/
https://ncbi.nlm.nih.gov/pubmed/21921694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.7.12.17893
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