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Ambra1: A Parkin-binding protein involved in mitophagy
Mutations in the gene for the E3 ubiquitin ligase Parkin are the most prevalent cause of autosomal recessive Parkinson disease (PD), an incurable neurodegenerative disorder. Parkin surveys mitochondrial quality by translocating to depolarized mitochondria and inducing their selective macroautophagic...
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| Main Authors: | , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Landes Bioscience
2011
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3327619/ https://ncbi.nlm.nih.gov/pubmed/21921694 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.7.12.17893 |
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