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Ambra1: A Parkin-binding protein involved in mitophagy

Mutations in the gene for the E3 ubiquitin ligase Parkin are the most prevalent cause of autosomal recessive Parkinson disease (PD), an incurable neurodegenerative disorder. Parkin surveys mitochondrial quality by translocating to depolarized mitochondria and inducing their selective macroautophagic...

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Detalles Bibliográficos
Main Authors: Van Humbeeck, Cindy, Cornelissen, Tom, Vandenberghe, Wim
Formato: Artigo
Idioma:Inglês
Publicado: Landes Bioscience 2011
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3327619/
https://ncbi.nlm.nih.gov/pubmed/21921694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.7.12.17893
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