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Ambra1: A Parkin-binding protein involved in mitophagy

Mutations in the gene for the E3 ubiquitin ligase Parkin are the most prevalent cause of autosomal recessive Parkinson disease (PD), an incurable neurodegenerative disorder. Parkin surveys mitochondrial quality by translocating to depolarized mitochondria and inducing their selective macroautophagic...

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Bibliografiske detaljer
Main Authors: Van Humbeeck, Cindy, Cornelissen, Tom, Vandenberghe, Wim
Format: Artigo
Sprog:Inglês
Udgivet: Landes Bioscience 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3327619/
https://ncbi.nlm.nih.gov/pubmed/21921694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.7.12.17893
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