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A subunit of coatomer protein complex offers a novel tumor-specific target through a surprising mechanism
COPI, a coatomer protein complex of secretory vesicles, is involved in Golgi and endoplasmic reticulum traffic and in early endosome maturation. The loss of COPI results in the fragmentation of Golgi, accumulation of immature autophagosomes, inhibition of autophagy, and cell death. Since COPI is req...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3327618/ https://ncbi.nlm.nih.gov/pubmed/22024755 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.7.12.17659 |
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