Effective Radiovirotherapy for Malignant Gliomas by Using Oncolytic Measles Virus Strains Encoding the Sodium Iodide Symporter (MV-NIS)

Engineered measles virus (MV) strains deriving from the vaccine lineage represent a promising oncolytic platform and are currently being tested in phase I trials. In this study, we have demonstrated that MV strains genetically engineered to express the human sodium iodide symporter (NIS) have signif...

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Hlavní autoři: Opyrchal, Mateusz, Allen, Cory, Iankov, Ianko, Aderca, Ileana, Schroeder, Mark, Sarkaria, Jann, Galanis, Evanthia
Médium: Artigo
Jazyk:Inglês
Vydáno: Mary Ann Liebert, Inc. 2011
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3327604/
https://ncbi.nlm.nih.gov/pubmed/22185260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2011.158
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