Nalaganje...

Inhibition of connective tissue growth factor by small interfering ribonucleic acid prevents increase in extracellular matrix molecules in a rodent model of diabetic retinopathy

PURPOSE: Connective tissue growth factor (CTGF) is a profibrotic factor that induces extracellular matrix (ECM) production and angiogenesis, two processes involved in diabetic retinopathy (DR). In this study, we examined whether insulin therapy or a CTGF-specific small interfering RNA (siRNA) admini...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Winkler, Jennifer L., Kedees, Mamdouh H., Guz, Yelena, Teitelman, Gladys
Format: Artigo
Jezik:Inglês
Izdano: Molecular Vision 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3327439/
https://ncbi.nlm.nih.gov/pubmed/22511849
Oznake: Označite
Brez oznak, prvi označite!