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The endosomal adaptor protein APPL1 impairs the turnover of leading edge adhesions to regulate cell migration

Cell migration is a complex process that requires the integration of signaling events that occur in distinct locations within the cell. Adaptor proteins, which can localize to different subcellular compartments, where they bring together key signaling proteins, are emerging as attractive candidates...

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Main Authors: Broussard, Joshua A., Lin, Wan-hsin, Majumdar, Devi, Anderson, Bridget, Eason, Brady, Brown, Claire M., Webb, Donna J.
格式: Artigo
語言:Inglês
出版: The American Society for Cell Biology 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3327316/
https://ncbi.nlm.nih.gov/pubmed/22379109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E11-02-0124
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