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An APPL1/Akt Signaling Complex Regulates Dendritic Spine and Synapse Formation in Hippocampal Neurons
The formation and plasticity of dendritic spines and synapses, which are poorly understood on a molecular level, are critical for cognitive functions, such as learning and memory. The adaptor protein containing PH domain, PTB domain, and leucine zipper motif (APPL1) is emerging as a critical regulat...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3046229/ https://ncbi.nlm.nih.gov/pubmed/21236345 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mcn.2011.01.003 |
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