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An APPL1/Akt Signaling Complex Regulates Dendritic Spine and Synapse Formation in Hippocampal Neurons

The formation and plasticity of dendritic spines and synapses, which are poorly understood on a molecular level, are critical for cognitive functions, such as learning and memory. The adaptor protein containing PH domain, PTB domain, and leucine zipper motif (APPL1) is emerging as a critical regulat...

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Detalhes bibliográficos
Main Authors: Majumdar, Devi, Nebhan, Caroline A., Hu, Lan, Anderson, Bridget, Webb, Donna J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3046229/
https://ncbi.nlm.nih.gov/pubmed/21236345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mcn.2011.01.003
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