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N-WASP and the Arp2/3 Complex Are Critical Regulators of Actin in the Development of Dendritic Spines and Synapses

Changes in the number, size, and shape of dendritic spines are associated with synaptic plasticity, which underlies cognitive functions such as learning and memory. This plasticity is attributed to reorganization of actin, but the molecular signals that regulate this process are poorly understood. I...

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Hlavní autoři: Wegner, Adam M., Nebhan, Caroline A., Hu, Lan, Majumdar, Devi, Meier, Kristen M., Weaver, Alissa M., Webb, Donna J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2414292/
https://ncbi.nlm.nih.gov/pubmed/18430734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M801555200
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