Silencing of the TGF-β1 Gene Increases the Immunogenicity of Cells from Human Ovarian Carcinoma

Cells from many tumors produce transforming growth factor (TGF)-βwhich facilitates their escape from control by the immune system. We previously reported that non-immunogenic cells from either of two transplantable mouse tumors became effective as therapeutic tumor vaccines after lentivirus-mediated...

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Bibliografiske detaljer
Main Authors: Wei, Huafeng, Liu, Pu, Swisher, Elizabeth, Yip, Yuen Yee, Tse, Jee Hang, Agnew, Kathy, Hellström, Karl Erik, Hellström, Ingegerd
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3327124/
https://ncbi.nlm.nih.gov/pubmed/22421944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CJI.0b013e31824d72ee
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