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Detection of the HE4 Protein in Urine as a Biomarker for Ovarian Neoplasms

The HE4 protein is overexpressed in ovarian carcinomas and can be detected in serum by an ELISA with sensitivity similar to CA125 and higher specificity for malignant disease. We now demonstrate that HE4 can also be detected in the urine at a specificity level of 94.4%, including 13/15 (86.6%) with...

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Detalhes bibliográficos
Main Authors: Hellstrom, Ingegerd, Heagerty, Patrick J., Swisher, Elizabeth M., Liu, Pu, Jaffar, Jade, Agnew, Kathy, Hellstrom, Karl Erik
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3156592/
https://ncbi.nlm.nih.gov/pubmed/20381233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2010.03.013
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