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DETECTING GENOME-WIDE HAPLOTYPE POLYMORPHISM BY COMBINED USE OF MENDELIAN CONSTRAINTS AND LOCAL POPULATION STRUCTURE

Data from current gene-disease association studies motivate changes to existing haplotype inference methodologies. Many datasets are now comprised of both pedigree and population data so it is desirable to incorporate both sources of information when inferring haplotypes. The availability of high-de...

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Autori principali: LI, XIN, CHEN, YIXUAN, LI, JING
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3326656/
https://ncbi.nlm.nih.gov/pubmed/19908387
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