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Detecting Structure of Haplotypes and Local Ancestry
We present a two-layer hidden Markov model to detect the structure of haplotypes for unrelated individuals. This allows us to model two scales of linkage disequilibrium (one within a group of haplotypes and one between groups), thereby taking advantage of rich haplotype information to infer local an...
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| Autor principal: | |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Genetics Society of America
2014
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3948796/ https://ncbi.nlm.nih.gov/pubmed/24388880 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.113.160697 |
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