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Interrogating local population structure for fine mapping in genome-wide association studies
Motivation: Adjustment for population structure is necessary to avoid bias in genetic association studies of susceptibility variants for complex diseases. Population structure may differ from one genomic region to another due to the variability of individual ancestry associated with migration, rando...
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| Hlavní autoři: | , , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Oxford University Press
2010
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2982153/ https://ncbi.nlm.nih.gov/pubmed/20889494 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btq560 |
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