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Interrogating local population structure for fine mapping in genome-wide association studies

Motivation: Adjustment for population structure is necessary to avoid bias in genetic association studies of susceptibility variants for complex diseases. Population structure may differ from one genomic region to another due to the variability of individual ancestry associated with migration, rando...

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Podrobná bibliografie
Hlavní autoři: Qin, Huaizhen, Morris, Nathan, Kang, Sun J., Li, Mingyao, Tayo, Bamidele, Lyon, Helen, Hirschhorn, Joel, Cooper, Richard S., Zhu, Xiaofeng
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2982153/
https://ncbi.nlm.nih.gov/pubmed/20889494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btq560
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