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Interrogating local population structure for fine mapping in genome-wide association studies

Motivation: Adjustment for population structure is necessary to avoid bias in genetic association studies of susceptibility variants for complex diseases. Population structure may differ from one genomic region to another due to the variability of individual ancestry associated with migration, rando...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Qin, Huaizhen, Morris, Nathan, Kang, Sun J., Li, Mingyao, Tayo, Bamidele, Lyon, Helen, Hirschhorn, Joel, Cooper, Richard S., Zhu, Xiaofeng
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2982153/
https://ncbi.nlm.nih.gov/pubmed/20889494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btq560
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