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Mutational analysis of a phenazine biosynthetic gene cluster in Streptomyces anulatus 9663

The biosynthetic gene cluster for endophenazines, i.e., prenylated phenazines from Streptomyces anulatus 9663, was heterologously expressed in several engineered host strains derived from Streptomyces coelicolor M145. The highest production levels were obtained in strain M512. Mutations in the rpoB...

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Autors principals: Saleh, Orwah, Flinspach, Katrin, Westrich, Lucia, Kulik, Andreas, Gust, Bertolt, Fiedler, Hans-Peter, Heide, Lutz
Format: Artigo
Idioma:Inglês
Publicat: Beilstein-Institut 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3326630/
https://ncbi.nlm.nih.gov/pubmed/22509222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.8.57
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