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Heterologous Expression of Novobiocin and Clorobiocin Biosynthetic Gene Clusters
A method was developed for the heterologous expression of biosynthetic gene clusters in different Streptomyces strains and for the modification of these clusters by single or multiple gene replacements or gene deletions with unprecedented speed and versatility. λ-Red-mediated homologous recombinatio...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1087579/ https://ncbi.nlm.nih.gov/pubmed/15870333 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.71.5.2452-2459.2005 |
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