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Heterologous Expression of Novobiocin and Clorobiocin Biosynthetic Gene Clusters
A method was developed for the heterologous expression of biosynthetic gene clusters in different Streptomyces strains and for the modification of these clusters by single or multiple gene replacements or gene deletions with unprecedented speed and versatility. λ-Red-mediated homologous recombinatio...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Microbiology
2005
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1087579/ https://ncbi.nlm.nih.gov/pubmed/15870333 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.71.5.2452-2459.2005 |
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