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3-(N-Arylsulfamoyl)benzamides, Inhibitors of Human Sirtuin Type 2 (SIRT2)
Inhibition of sirtuin 2 (SIRT2) is known to be protective against the toxicity of disease proteins in Parkinson’s and Huntington’s models of neurodegeneration. Previously, we developed SIRT2 inhibitors based on the 3-(N-arylsulfamoyl)benzamide scaffold, including 3-(N-(4-bromophenyl)sulfamoyl)-N-(4-...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3326608/ https://ncbi.nlm.nih.gov/pubmed/22446090 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2012.02.089 |
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