Targeting cholesterol-rich microdomains to circumvent tamoxifen-resistant breast cancer

INTRODUCTION: Adjuvant treatment with tamoxifen substantially improves survival of women with estrogen-receptor positive (ER+) tumors. Tamoxifen resistance (TAMR) limits clinical benefit. RRR-α-tocopherol ether-linked acetic acid analogue (α-TEA) is a small bioactive lipid with potent anticancer act...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Tiwary, Richa, Yu, Weiping, deGraffenried, Linda A, Sanders, Bob G, Kline, Kimberly
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2011
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3326562/
https://ncbi.nlm.nih.gov/pubmed/22115051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr3063
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