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Targeting cholesterol-rich microdomains to circumvent tamoxifen-resistant breast cancer
INTRODUCTION: Adjuvant treatment with tamoxifen substantially improves survival of women with estrogen-receptor positive (ER+) tumors. Tamoxifen resistance (TAMR) limits clinical benefit. RRR-α-tocopherol ether-linked acetic acid analogue (α-TEA) is a small bioactive lipid with potent anticancer act...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3326562/ https://ncbi.nlm.nih.gov/pubmed/22115051 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr3063 |
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