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Single-molecule observation of helix staggering, sliding, and coiled coil misfolding
The biological functions of coiled coils generally depend on efficient folding and perfect pairing of their α-helices. Dynamic changes in the helical registry that lead to staggered helices have only been proposed for a few special systems and not found in generic coiled coils. Here, we report our o...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3326506/ https://ncbi.nlm.nih.gov/pubmed/22451899 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1116784109 |
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