p75 neurotrophin receptor regulates glucose homeostasis and insulin sensitivity

Insulin resistance is a key factor in the etiology of type 2 diabetes. Insulin-stimulated glucose uptake is mediated by the glucose transporter 4 (GLUT4), which is expressed mainly in skeletal muscle and adipose tissue. Insulin-stimulated translocation of GLUT4 from its intracellular compartment to...

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Autori principali: Baeza-Raja, Bernat, Li, Pingping, Le Moan, Natacha, Sachs, Benjamin D., Schachtrup, Christian, Davalos, Dimitrios, Vagena, Eirini, Bridges, Dave, Kim, Choel, Saltiel, Alan R., Olefsky, Jerrold M., Akassoglou, Katerina
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2012
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3326459/
https://ncbi.nlm.nih.gov/pubmed/22460790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1103638109
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