p75 neurotrophin receptor regulates energy balance in obesity

Obesity and metabolic syndrome reflect the dysregulation of molecular pathways that control energy homeostasis. Here we show that upon high-fat diet (HFD), the p75 neurotrophin receptor (p75(NTR)) controls energy expenditure in obese mice. Despite no changes in food intake, p75(NTR)-null mice were p...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Baeza-Raja, Bernat, Sachs, Benjamin D., Li, Pingping, Christian, Frank, Vagena, Eirini, Davalos, Dimitrios, Le Moan, Natacha, Ryu, Jae Kyu, Sikorski, Shoana L., Chan, Justin P., Scadeng, Miriam, Taylor, Susan S., Houslay, Miles D., Baillie, George S., Saltiel, Alan R., Olefsky, Jerrold M., Akassoglou, Katerina
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4831919/
https://ncbi.nlm.nih.gov/pubmed/26748707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.12.028
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