p75 neurotrophin receptor regulates energy balance in obesity

Obesity and metabolic syndrome reflect the dysregulation of molecular pathways that control energy homeostasis. Here we show that upon high-fat diet (HFD), the p75 neurotrophin receptor (p75(NTR)) controls energy expenditure in obese mice. Despite no changes in food intake, p75(NTR)-null mice were p...

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發表在:Cell Rep
Main Authors: Baeza-Raja, Bernat, Sachs, Benjamin D., Li, Pingping, Christian, Frank, Vagena, Eirini, Davalos, Dimitrios, Le Moan, Natacha, Ryu, Jae Kyu, Sikorski, Shoana L., Chan, Justin P., Scadeng, Miriam, Taylor, Susan S., Houslay, Miles D., Baillie, George S., Saltiel, Alan R., Olefsky, Jerrold M., Akassoglou, Katerina
格式: Artigo
語言:Inglês
出版: 2015
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4831919/
https://ncbi.nlm.nih.gov/pubmed/26748707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.12.028
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