p75 neurotrophin receptor regulates energy balance in obesity

Obesity and metabolic syndrome reflect the dysregulation of molecular pathways that control energy homeostasis. Here we show that upon high-fat diet (HFD), the p75 neurotrophin receptor (p75(NTR)) controls energy expenditure in obese mice. Despite no changes in food intake, p75(NTR)-null mice were p...

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Publicat a:Cell Rep
Autors principals: Baeza-Raja, Bernat, Sachs, Benjamin D., Li, Pingping, Christian, Frank, Vagena, Eirini, Davalos, Dimitrios, Le Moan, Natacha, Ryu, Jae Kyu, Sikorski, Shoana L., Chan, Justin P., Scadeng, Miriam, Taylor, Susan S., Houslay, Miles D., Baillie, George S., Saltiel, Alan R., Olefsky, Jerrold M., Akassoglou, Katerina
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4831919/
https://ncbi.nlm.nih.gov/pubmed/26748707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.12.028
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