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Structural and Biochemical Characterization of the Childhood Cataract-associated R76S Mutant of Human γD-Crystallin
Although a number of γD-crystallin mutations are associated with cataract formation, there is not a clear understanding of the molecular mechanism(s) that lead to this protein deposition disease. As part of our ongoing studies on crystallins, we investigated the recently discovered Arg76 to Ser (R76...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3326406/ https://ncbi.nlm.nih.gov/pubmed/22394327 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi300199d |
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