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Domain Swapping Proceeds via Complete Unfolding: A (19)F- and (1)H- NMR Study of the Cyanovirin-N Protein

Domain swapping creates protein oligomers by exchange of structural units between identical monomers. At present, no unifying molecular mechanism of domain swapping has emerged. Here we used the protein Cyanovirin-N and (19)F-NMR to investigate the process of domain swapping. CV-N is an HIV inactiva...

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Autori principali: Liu, Lin, Byeon, In-Ja L., Bahar, Ivet, Gronenborn, Angela M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3326405/
https://ncbi.nlm.nih.gov/pubmed/22296296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja210118w
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