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Correction of RT–qPCR data for genomic DNA-derived signals with ValidPrime

Genomic DNA (gDNA) contamination is an inherent problem during RNA purification that can lead to non-specific amplification and aberrant results in reverse transcription quantitative PCR (RT—qPCR). Currently, there is no alternative to RT(−) controls to evaluate the impact of the gDNA background on...

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Detalhes bibliográficos
Main Authors: Laurell, Henrik, Iacovoni, Jason S., Abot, Anne, Svec, David, Maoret, Jean-José, Arnal, Jean-François, Kubista, Mikael
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3326333/
https://ncbi.nlm.nih.gov/pubmed/22228834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr1259
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