Deletion of FoxN1 in the Thymic Medullary Epithelium Reduces Peripheral T Cell Responses to Infection and Mimics Changes of Aging

Aging increases susceptibility to infection, in part because thymic involution culminates in reduced naïve T-lymphocyte output. Thymic epithelial cells (TECs) are critical to ensure normal maturation of thymocytes and production of peripheral T cells. The forkhead-class transcription factor, encoded...

全面介紹

Na minha lista:
書目詳細資料
Main Authors: Guo, Jianfei, Feng, Yan, Barnes, Peter, Huang, Fang-Fang, Idell, Steven, Su, Dong-Ming, Shams, Homayoun
格式: Artigo
語言:Inglês
出版: Public Library of Science 2012
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3326029/
https://ncbi.nlm.nih.gov/pubmed/22514652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0034681
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!

相似書籍