The Notch Ligand Delta-Like 4 Regulates Multiple Stages of Early Hemato-Vascular Development

BACKGROUND: In mouse embryos, homozygous or heterozygous deletions of the gene encoding the Notch ligand Dll4 result in early embryonic death due to major defects in endothelial remodeling in the yolk sac and embryo. Considering the close developmental relationship between endothelial and hematopoie...

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Hlavní autoři: Laranjeiro, Ricardo, Alcobia, Isabel, Neves, Hélia, Gomes, Andreia C., Saavedra, Pedro, Carvalho, Catarina C., Duarte, António, Cidadão, António, Parreira, Leonor
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2012
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3326024/
https://ncbi.nlm.nih.gov/pubmed/22514637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0034553
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