Differential Effects of Notch Ligands Delta-1 and Jagged-1 in Human Lymphoid Differentiation

Notch signaling is known to differentially affect the development of lymphoid B and T cell lineages, but it remains unclear whether such effects are specifically dependent on distinct Notch ligands. Using a cell coculture assay we observed that the Notch ligand Delta-1 completely inhibits the differ...

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Bibliografiske detaljer
Main Authors: Jaleco, Ana C., Neves, Hélia, Hooijberg, Erik, Gameiro, Paula, Clode, Nuno, Haury, Matthias, Henrique, Domingos, Parreira, Leonor
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2001
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193482/
https://ncbi.nlm.nih.gov/pubmed/11581320
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