Acute Activation of AMP-Activated Protein Kinase Prevents H(2)O(2)-Induced Premature Senescence in Primary Human Keratinocytes

We investigated the effects of AMPK on H(2)O(2)-induced premature senescence in primary human keratinocytes. Incubation with 50 µM H(2)O(2) for 2 h resulted in premature senescence with characteristic increases in senescence-associated ß-galactosidase (SA-gal) staining 3 days later and no changes in...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Ido, Yasuo, Duranton, Albert, Lan, Fan, Cacicedo, Jose M., Chen, Tai C., Breton, Lionel, Ruderman, Neil B.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2012
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3325987/
https://ncbi.nlm.nih.gov/pubmed/22514710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0035092
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky