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Acute Activation of AMP-Activated Protein Kinase Prevents H(2)O(2)-Induced Premature Senescence in Primary Human Keratinocytes
We investigated the effects of AMPK on H(2)O(2)-induced premature senescence in primary human keratinocytes. Incubation with 50 µM H(2)O(2) for 2 h resulted in premature senescence with characteristic increases in senescence-associated ß-galactosidase (SA-gal) staining 3 days later and no changes in...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Public Library of Science
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3325987/ https://ncbi.nlm.nih.gov/pubmed/22514710 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0035092 |
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