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Downregulation of HuR as a new mechanism of doxorubicin resistance in breast cancer cells
BACKGROUND: HuR, an RNA binding protein involved in the post-transcriptional regulation of a wide spectrum of mRNAs, has been demonstrated to be a determinant of carcinogenesis and tumor aggressiveness in several cancer types. In this study, we investigated the role of HuR in the apoptosis and in th...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
BioMed Central
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3325864/ https://ncbi.nlm.nih.gov/pubmed/22436134 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-11-13 |
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