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Downregulation of HuR as a new mechanism of doxorubicin resistance in breast cancer cells

BACKGROUND: HuR, an RNA binding protein involved in the post-transcriptional regulation of a wide spectrum of mRNAs, has been demonstrated to be a determinant of carcinogenesis and tumor aggressiveness in several cancer types. In this study, we investigated the role of HuR in the apoptosis and in th...

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Dettagli Bibliografici
Autori principali: Latorre, Elisa, Tebaldi, Toma, Viero, Gabriella, Spartà, Antonino Maria, Quattrone, Alessandro, Provenzani, Alessandro
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3325864/
https://ncbi.nlm.nih.gov/pubmed/22436134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-11-13
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