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Crystal structure of peptidyl-tRNA hydrolase from mycobacterium smegmatis reveals novel features related to enzyme dynamics

Peptidyl-tRNA hydrolase from Mycobacterium smegmatis is a single domain 21 kDa protein involved in the hydrolysis of prematurely produced peptidyl-tRNAs to ensure the viability of cells in bacteria, thus making it a potentially important drug target. In order to aid the development of potent drugs f...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kumar, Ashok, Singh, Nagendra, Yadav, Rahul, Kumar, Ramasamy P., Sharma, Sujata, Arora, Ashish, Singh, T. P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: e-Century Publishing Corporation 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3325776/
https://ncbi.nlm.nih.gov/pubmed/22509481
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