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Long-distance correlations of rhinovirus capsid dynamics contribute to uncoating and antiviral activity
Human rhinovirus (HRV) and other members of the enterovirus genus bind small-molecule antiviral compounds in a cavity buried within the viral capsid protein VP1. These compounds block the release of the viral protein VP4 and RNA from inside the capsid during the uncoating process. In addition, the a...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3325699/ https://ncbi.nlm.nih.gov/pubmed/22440750 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1119174109 |
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