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Dissociation of an antiviral compound from the internal pocket of human rhinovirus 14 capsid
WIN antiviral compounds bind human rhinovirus, as well as enterovirus and parechovirus, in an internal cavity located within the viral protein capsid. Access to the buried pocket necessitates deviation from the average viral protein structure identified by crystallography. We investigated the dissoc...
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| Autores principales: | , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
2005
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1140408/ https://ncbi.nlm.nih.gov/pubmed/15899980 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0408749102 |
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