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Dissociation of an antiviral compound from the internal pocket of human rhinovirus 14 capsid

WIN antiviral compounds bind human rhinovirus, as well as enterovirus and parechovirus, in an internal cavity located within the viral protein capsid. Access to the buried pocket necessitates deviation from the average viral protein structure identified by crystallography. We investigated the dissoc...

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Detaylı Bibliyografya
Asıl Yazarlar: Li, Yumin, Zhou, Zhigang, Post, Carol Beth
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2005
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1140408/
https://ncbi.nlm.nih.gov/pubmed/15899980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0408749102
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