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Long-distance correlations of rhinovirus capsid dynamics contribute to uncoating and antiviral activity

Human rhinovirus (HRV) and other members of the enterovirus genus bind small-molecule antiviral compounds in a cavity buried within the viral capsid protein VP1. These compounds block the release of the viral protein VP4 and RNA from inside the capsid during the uncoating process. In addition, the a...

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Hlavní autoři: Roy, Amitava, Post, Carol Beth
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3325699/
https://ncbi.nlm.nih.gov/pubmed/22440750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1119174109
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