Discovery of Regulatory Elements in Human ATP-Binding Cassette Transporters through Expression Quantitative Trait Mapping

ATP-Binding Cassette (ABC) membrane transporters determine the disposition of many drugs, metabolites and endogenous compounds. Coding region variation in ABC transporters is the cause of many genetic disorders, but much less is known about the genetic basis and functional outcome of ABC transporter...

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Detalhes bibliográficos
Main Authors: Matsson, Pär, Yee, Sook Wah, Markova, Svetlana, Morrissey, Kari, Jenkins, Gerard, Xuan, Jiekun, Jorgenson, Eric, Kroetz, Deanna L., Giacomini, Kathleen M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3325368/
https://ncbi.nlm.nih.gov/pubmed/21383772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tpj.2011.8
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