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Biophysical Approaches Facilitate Computational Drug Discovery for ATP-Binding Cassette Proteins
Although membrane proteins represent most therapeutically relevant drug targets, the availability of atomic resolution structures for this class of proteins has been limited. Structural characterization has been hampered by the biophysical nature of these polytopic transporters, receptors, and chann...
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| Veröffentlicht in: | Int J Med Chem |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Hindawi
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5376479/ https://ncbi.nlm.nih.gov/pubmed/28409029 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/1529402 |
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