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Phospholamban Mutants Compete with Wild Type for SERCA Binding in Living Cells
We have used fluorescent fusion proteins stably expressed in HEK cells to detect directly the interaction between the sarcoplasmic reticulum Ca-ATPase (SERCA) and phospholamban (PLB) in living cells, in order to design PLB mutants for gene therapy. Ca(2+) cycling in muscle cells depends strongly on...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3324857/ https://ncbi.nlm.nih.gov/pubmed/22405774 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2012.02.125 |
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