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Antigen Recognition is Facilitated by Invadosome-Like Protrusions Formed by Memory/Effector T Cells

Adaptive immunity requires that T cells efficiently scan diverse cell surfaces in order to identify cognate antigen. However, the basic cellular mechanisms remain unclear. Here we investigated this process using vascular endothelial cells, antigen presenting (APC) cells that possess a unique and ext...

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Detalhes bibliográficos
Main Authors: Sage, Peter T., Varghese, Laya M., Martinelli, Roberta, Sciuto, Tracey E., Kamei, Masataka, Dvorak, Ann M., Springer, Timothy A., Sharpe, Arlene H., Carman, Christopher V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3324627/
https://ncbi.nlm.nih.gov/pubmed/22442443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1102594
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