Release of cellular tension signals self-restorative ventral lamellipodia to heal barrier micro-wounds

Basic mechanisms by which cellular barriers sense and respond to integrity disruptions remain poorly understood. Despite its tenuous structure and constitutive exposure to disruptive strains, the vascular endothelium exhibits robust barrier function. We show that in response to micrometer-scale disr...

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Main Authors: Martinelli, Roberta, Kamei, Masataka, Sage, Peter T., Massol, Ramiro, Varghese, Laya, Sciuto, Tracey, Toporsian, Mourad, Dvorak, Ann M., Kirchhausen, Tomas, Springer, Timothy A., Carman, Christopher V.
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2013
Teme:
Research Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3639391/
https://ncbi.nlm.nih.gov/pubmed/23629967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201209077
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