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HandAlign: Bayesian multiple sequence alignment, phylogeny and ancestral reconstruction

Summary: We describe handalign, a software package for Bayesian reconstruction of phylogenetic history. The underlying model of sequence evolution describes indels and substitutions. Alignments, trees and model parameters are all treated as jointly dependent random variables and sampled via Metropol...

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Detalhes bibliográficos
Main Authors: Westesson, Oscar, Barquist, Lars, Holmes, Ian
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3324510/
https://ncbi.nlm.nih.gov/pubmed/22285828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bts058
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