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Historian: accurate reconstruction of ancestral sequences and evolutionary rates

MOTIVATION: Reconstruction of ancestral sequence histories, and estimation of parameters like indel rates, are improved by using explicit evolutionary models and summing over uncertain alignments. The previous best tool for this purpose (according to simulation benchmarks) was ProtPal, but this tool...

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Dades bibliogràfiques
Publicat a:Bioinformatics
Autor principal: Holmes, Ian H
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6074814/
https://ncbi.nlm.nih.gov/pubmed/28104629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btw791
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