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Historian: accurate reconstruction of ancestral sequences and evolutionary rates

MOTIVATION: Reconstruction of ancestral sequence histories, and estimation of parameters like indel rates, are improved by using explicit evolutionary models and summing over uncertain alignments. The previous best tool for this purpose (according to simulation benchmarks) was ProtPal, but this tool...

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Bibliografiske detaljer
Udgivet i:Bioinformatics
Hovedforfatter: Holmes, Ian H
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6074814/
https://ncbi.nlm.nih.gov/pubmed/28104629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btw791
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