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An experimental phylogeny to benchmark ancestral sequence reconstruction

Ancestral sequence reconstruction (ASR) is a still-burgeoning method that has revealed many key mechanisms of molecular evolution. One criticism of the approach is an inability to validate its algorithms within a biological context as opposed to a computer simulation. Here we build an experimental p...

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Pubblicato in:Nat Commun
Autori principali: Randall, Ryan N., Radford, Caelan E., Roof, Kelsey A., Natarajan, Divya K., Gaucher, Eric A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5027606/
https://ncbi.nlm.nih.gov/pubmed/27628687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12847
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