Mixed Adjuvant Formulations Reveal a New Combination That Elicit Antibody Response Comparable to Freund's Adjuvants

Adjuvant formulations capable of inducing high titer and high affinity antibody responses would provide a major advance in the development of vaccines to viral infections such as HIV-1. Although oil-in-water emulsions, such as Freund's adjuvant (FCA/FIA), are known to be potent, their toxicity...

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Autors principals: Lai, Rachel P. J., Seaman, Michael S., Tonks, Paul, Wegmann, Frank, Seilly, David J., Frost, Simon D. W., LaBranche, Celia C., Montefiori, David C., Dey, Antu K., Srivastava, Indresh K., Sattentau, Quentin, Barnett, Susan W., Heeney, Jonathan L.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3324409/
https://ncbi.nlm.nih.gov/pubmed/22509385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0035083
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