NGF promotes cell cycle progression by regulating D-type cyclins via PI3K/Akt and MAPK/Erk activation in human corneal epithelial cells

PURPOSE: Nerve growth factor (NGF) plays an important role in promoting the healing of corneal wounds. However, the molecular mechanism by which NGF functions is unknown. We investigated the possible effects of NGF on phosphatidylinositol 3-kinase (PI3K)/protein kinase B (Akt) and mitogen activated...

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Détails bibliographiques
Auteurs principaux: Hong, Jiaxu, Qian, Tingting, Le, Qihua, Sun, Xinghuai, Wu, Jihong, Chen, Junyi, Yu, Xiaobo, Xu, Jianjiang
Format: Artigo
Langue:Inglês
Publié: Molecular Vision 2012
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3324366/
https://ncbi.nlm.nih.gov/pubmed/22509106
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